Vein wrapping facilitates basic fibroblast growth factor-induced heme oxygenase-1 expression following chronic nerve constriction injury

Homocysteine Induces Heme Oxygenase-1 Expression via Transcription Factor Nrf2 Activation in HepG2 Cells

Background: Elevated level of plasma homocysteine has been related to various diseases. Patients with hyperhomocysteinemia can develop hepatic steatosis and fibrosis. We hypothesized that oxidative stress induced by homocysteine might play an important role in pathogenesis of liver injury. Also, the cellular response designed to combat oxidative stress is primarily controlled by the transcripti...

Basic fibroblast growth factor expression precedes flow-induced arterial enlargement.

Arteries enlarge in response to increased blood flow, but the molecular signals controlling this enlargement are not well understood. Basic fibroblast growth factor (bFGF) is a potent mitogen for endothelial cells (EC) and smooth muscle cells (SMC) and promotes cellular proliferation and differentiation. In order to determine whether bFGF is expressed in response to increased blood flow in vivo...

Heme Oxygenase-1 and Acute Kidney Injury following Cardiac Surgery.

BACKGROUND Intraoperative hemolysis and inflammation are associated with acute kidney injury (AKI) following cardiac surgery. Plasma-free hemoglobin induces heme oxygenase-1 (HO-1) expression. HO-1 degrades heme but increases in experimental models of AKI. This study tested the hypothesis that plasma HO-1 concentrations are associated with intraoperative hemolysis and are increased in patients ...

homocysteine induces heme oxygenase-1 expression via transcription factor nrf2 activation in hepg2 cells

background: elevated level of plasma homocysteine has been related to various diseases. patients with hyperhomocysteinemia can develop hepatic steatosis and fibrosis. we hypothesized that oxidative stress induced by homocysteine might play an important role in pathogenesis of liver injury. also, the cellular response designed to combat oxidative stress is primarily controlled by the transcripti...

heme oxygenase-1 mrna expression in egyptian patients with chronic liver disease